MDMA increases activity of serotonin, dopamine, and norepinephrine in the brain — especially serotonin, which regulates mood, empathy, and connection.
Effects of MDMA
Positive (usually 30–60 minutes after ingestion):
Intense feelings of euphoria and emotional warmth
Increased empathy, bonding, and openness (aka the “love drug”) Heightened sensory perception (e.g., music and touch feel amazing) Boost in energy and sociability
Duration:
Onset: 30–60 minutes
Peak: 2–3 hours
Afterglow: 2–4 hours
Total Duration: 4–6 hours
Comedown: Can involve fatigue, mood dip (aka “Tuesday blues”)









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